Toss the pork with the salt, pepper, brown sugar, garlic powder, onion powder, dried mustard, smoked paprika, and cayenne pepper.
Add all the BBQ sauce ingredients to a bowl and stir to combine.
Turn your Instant Pot on to the Sauté function. Once the pot is hot, add the olive oil, Sear the pork on all sides, working in batches as to not over-crowd the pot. Set the seared pieces aside in a bowl.
Pour the beer into the pot and whisk well to get all the bits off the bottom. Add the pork back to the pot, along with the prepared BBQ sauce. Give everything a quick stir to combine.
Secure the lid of your Instant Pot and set the valve to SEAL. Cook on high pressure for 40 minutes, then let the pressure release naturally for 15 minutes before quick-releasing the remaining pressure.
Remove the pieces of pork with a slotted spoon and transfer them to a baking sheet. Turn the sauté setting on your Instant Pot, and let the sauce reduce for 10-15 minutes, or until it has reached your desired consistency.**
Use two forks to shred the pork, removing any large pieces of fat during this process. OPTIONAL: Broil the pork in the oven for 5 minutes or so to crisp the edges.
Pour about 1 cup of sauce over the pork and toss well to combine. Leave some sauce on the side to serve.